After BSO treatment, there was an early decline in cellular glutathione (GSH), followed by an increase in reactive oxygen species (ROS) production, which induced a variety of apoptotic signals (detectable at different time points) in the absence of any external apoptotic stimuli
Older adults and those with compromised antioxidant systems may require lower starting doses with gradual titration based on tolerance and biomarker response
In the studies that proofed tumor growth inhibition by a KD fed ad libitum, there was a significant increase in KB levels, but not necessarily decreases in blood glucose levels or body weight
Without L-carnitine, these dietary fats cannot enter the mitochondrial matrix to undergo beta-oxidation, the biochemical process that breaks down fats to generate adenosine triphosphate (ATP), the universal energy currency of the human body
Altern Med Rev 2005
doi: 10.3390/ijms11020458